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MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.
Forewords by:
Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989
and
Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs
- Sales Rank: #4207526 in Books
- Brand: Brand: Cambridge University Press
- Published on: 2008-01-21
- Original language: English
- Number of items: 1
- Dimensions: 9.96" h x 1.26" w x 6.97" l, 2.94 pounds
- Binding: Hardcover
- 580 pages
- Used Book in Good Condition
Review
"It will be a valuable reading for both students who want to gain a better understanding of alternative mechanisms of gene regulation, and scientists who intend to investigate the role of miRNAs in their research projects."
Silvana Debernardi, The Quarterly Review of Biology
About the Author
Krishnarao Appasani is the Founder and Chief Executive Officer of Gene Expression Systems, a gene discovery company, focusing on functional genomics in cancer research. He is the Editor of RNA Interference: From Basic Science to Drug Development (2005).
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